Our expert says:
Cross-sensitivity is indeed a concern. Remember to remind your doctor when prescribing antibiotics.
Cross-reactivity may be greater between first-generation cephalosporins and penicillins than between second-, third-, or fourth-generation cephalosporins and penicillins. Cephalosporin-allergic patients may have cross-reactivity with determinants of the penicillins, with different cephalosporins, or may react to just a single cephalosporin.
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