Our expert says:
You can usefully take it as a good rule that there are no drugs which mix usefully with alcohol, and with antidepressants, they generally reduce the effectiveness of the drugs, and may increase side-effects such as drowsiness or incoordination. And of course in manic phases of bipolar disorder, alcohol tends to cause disinhibition, which isn't useful then !
I have been impressed by the initial information about Valdoxan, but haven't seen any specific information suggesting that it would combine better with alcohol.
Better to give yourself the best chance of recovery by limiting alcohol intake.
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