15 August 2011

Cystic fibrosis and supplementation

People with cystic fibrosis have a heightened need for fat-soluble vitamins and sodium. The use of enzyme replacement therapy also plays an important role. DietDoc explains.

The majority of people suffering from cystic fibrosis have an increased need for certain vitamins and sodium because this genetic disease is characterised by a lack of pancreatic enzymes, which in turn will result in poor absorption of most nutrients.

People with cystic fibrosis may thus primarily suffer from a lack of vitamins A, D and E. Vitamin K deficiency may also occur as a result of long-term use of antibiotics, concomitant liver involvement and general nutrient malabsorption.

  • Vitamin A: 3500 and 7000 International Units (IU) for women and 4500 to 9000 IU for men
  • Vitamin E: up to 30mg a day for both men and women
  • Vitamin D: 5-10mcg per day for adults
  • Vitamin K: up to 5mg twice a week for adults on long-term antibiotic therapy


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