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04 October 2006

Pomegranate juice protects brain

A daily glass of antioxidant-rich pomegranate juice could halve the build-up of harmful proteins linked to Alzheimer’s disease, says a new animal study from the USA.

A daily glass of antioxidant-rich pomegranate juice could halve the build-up of harmful proteins linked to Alzheimer’s disease, says a new animal study from the USA.

It is against the oxidative stress that the polyphenols appear to offer protection.

How the study was conducted
Hartman and his co-workers supplemented the diets of transgenic mice (APPsw/Tg2576) with pomegranate juice. This strain of mice are engineered to express an amyloid precursor protein (APP) that leads to an early onset of neurological degeneration and subsequently Alzheimer’s disease.

Neurobiology of Disease (doi: 10.1016/j.nbd.2006.08.006).

More study needed
Being the first study into the potential protective role of pomegranate concentrate and the antioxidant polyphenols contained within, significantly more study is needed.

Magic ingredient: polyphenols
The work follows a recent epidemiological study into the possible role of fruit and vegetable juices reducing the risk of Alzheimer’s (The American Journal of Medicine, Vol. 119, pp. 751-759), a result that was also linked to the polyphenol, rather than the vitamin content of the fruit and vegetables.


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