The 24-year study included almost 9 200 people, 393 of whom had a stroke and 504 of whom developed cerebrovascular disease during the study period.

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Reporting in the March 27 issue of Neurology, researchers found that people with two copies of the H63D genetic defect in the HFE gene were two to three times more likely to have a stroke than people without the defect.

It's estimated that about 25 percent of northern Europeans carry the H63D gene defect, and it may be even more common in southern Europeans.

The genetic defect was not associated with carotid atherosclerosis (hardening of the arteries in the neck and head), the researchers said.

Further research is needed to determine why this genetic defect appears to cause such a significant increase in stroke, they added. – (HealthDayNews)

March 2007
 

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