Gene transfer vs. impotence

Unlike gene therapy, gene transfer does not change the DNA or genetic code of cells. Instead, small pieces of DNA reach the nuclei of cells, causing them to boost production of particular proteins that help relax smooth muscle cells. These type of cells are found in the penis. Relaxing the smooth muscle cells allows the penis to fill with blood and become erect.

This study of 11 men with ED found that the gene transfer therapy was safe and well-tolerated. Improvements in erectile function were maintained through the 24 weeks of the study. The findings were published online today in the journal Human Gene Therapy. – (HealthDayNews)

December 2006