Researchers concluded that eating fewer kilojoules prevented activation of two signalling pathways associated with the growth and development of cancer, while a high-kilojoule diet activated the pathways.

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The study was presented at the annual meeting of the American Association for Cancer Research, in San Diego.

These results, while tested in a mouse model of skin cancer, are broadly applicable to epithelial cancers in other tissues," said senior author John DiGiovanni, director of the department of carcinogenesis at the University of Texas M.D. Anderson Cancer Centre.

The mice in the study had precancerous skin lesions called papillomas and were fed four different diets. Two groups of mice ate kilojoule -reduced diets (15 percent and 30 percent) while the two other groups ate diets in which 10 percent and 60 percent of kilojoule came from fat. – (HealthDay News)

April 2008

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