The same seems to be true when it comes to nerve cells and amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

Advertisement

Damaged or saved from degeneration
A multi-centre American study found that in mouse models of ALS, the nerve cells (neurons) involved in ALS can either be damaged or saved from degeneration by neighbouring non-neuronal cells.

The scientists, led by researchers at the University of California, San Diego School of Medicine, found that when neighbouring non-neuronal cells contain a genetic mutation associated with ALS, they can cause damage in normal motor neurons. These are nerve cells that control voluntary movement.

The degeneration of motor neurons in people with ALS results in progressive loss of muscle control, paralysis and ultimately death.

Motor neurons protected, rescued
But the study also found that when these neighbouring non-neuronal are normal, they protect or rescue motor neurons from degeneration when the motor neurons themselves have the ALS mutation.

The study appears in the Oct. 3 issue of Science.

In place of the Herculean task of replacing the huge, metre-long motor neurons damaged by ALS, it would be easier to replace some of the surrounding cells with normal cells. Based on our findings, this could potentially prevent the degeneration and death of motor neurons that would otherwise be targeted for premature death, senior author Don Cleveland, UCSD professor of medicine, says in a news release. - (HealthDayNews)

Read more:
Fat build-up clue to ALS?
Lou Gehrig's disease insight

 

Print this article on

Rate this article Poor 1 2 3 4 5 Excellent

JOBS

Civil Engineering Technician Gauteng - Johannesburg Accountant Gauteng - North/Sandton Financial Manager R550,000-600,000 Per Annum Central African Republic Financial Accountant R300,000-340,000 Per Annum Gauteng Treasury Specialist R500,000-630,000 Per Annum Gauteng - East Rand Credit Manager R300,000-400,000 Per Annum Mpumalanga Financial Manager R27,000-30,000 Per Month Gauteng - North/Sandton Delphi developers Gauteng - North/Sandton Find more jobs Register your CV Post a job