Working with colleagues at the University of Texas at Austin, British researchers from the University of Bath gave Roaccutane to adolescent mice over a six-week period and monitored the animals' behaviour. While there was no change in their physical abilities, the rodents spent more time being immobile in response to stress tests, which was interpreted as a sign of depression. The drug's maker, Roche, does include a warning about depression in packets, BBC News reported.

From 1992 until this month, Britain's drug regulatory agency has received 1,588 reports of suspected adverse events among people taking Roaccutane, including 25 people who died from suicide, the BBC reported.

The mouse study was published in the journal Neuropsychopharmacology. – (HealthDayNews)

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September 2006
 

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