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Prostate - Staging &grading of prostate cancer
Staging of prostate cancer
Last updated: Thursday, September 30, 2004
Once the diagnosis of prostate cancer has been made the disease has to be staged and graded. The stage refers to the extent and spread of the disease while the grade refers to the nature (aggressiveness) of the particular tumour. Staging will determine the extent of disease and provide important prognostic information that will influence the management decisions.

Staging investigations

  • PSA
  • X-rays of lumbar spine and pelvis
  • Chest X-ray
  • Radionuclitide bone scan
 
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TNM Staging system

T stage (extent of primary lesion)
  • T1 - tumour confined to prostate, not palpable or visible on TRUS
  • T2 - tumour palpable or visible on TRUS but confined to prostate
  • T3 - spread beyond the prostatic capsule
  • T3a - extracapsular spread only
  • T3b - involvement of the seminal vesicles
  • T4 - invasion into rectal wall, bladder neck or pelvic wall
N (Nodal) status
  • N0 - regional nodes not involved
  • N1 - regional nodes involved by tumour
M (Distant Metastases)
  • M0 - no distant metastases
  • M1 - distant metastases present

Read more:
Some cancers develop quickly
Chemo: Genetic factors at play


 
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