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Opioids Opioids can be used with other pain killers like paracetamol and NSAIDs. They can be categorised according to their effect: low, intermediate and high efficacy. |  | Low efficacy opioids Low-efficacy opiods include codeine and porpoxyfene. |  | Moderate efficacy opioids These opioids are effective against moderate pain, and in adequte doses also against more severe pain. |  | High efficacy opioids High efficacy opioids are mostly administered by injection. They include morphine, nalbuphine and pethidine. |
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