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Cholesterol - Cholesterol & heart disease
How lipids move around
Last updated: Monday, May 19, 2008
Body components, including the lipids, are continually being formed, used, degraded and replaced. This process entails transport of biological compounds between tissues, using the plasma as the main highway.

 
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For lipids, this poses a problem since they’re generally not water-soluble.

The transport problem has been solved by incorporating cholesterol and triglycerides into the lipoproteins, as described before. (See "Other lipids - phospholipids".) These lipoproteins are classified according to their density or protein content.

LDL and HDL are varieties of lipoproteins:

  • LDL stands for "low-density lipoprotein". Its main function is to carry cholesterol to tissues, where it is deposited for use, or, when levels are high, for storage. Because this function of LDL is so strongly associated with cardiovascular disease, it has become known as “bad cholesterol”.
  • HDL, by contrast, stands for a "high-density lipoprotein". It is known as “good cholesterol” because its work is to remove excess cholesterol from tissues, and to transport it back to the liver for disposal.

Reviewed by Dr A.G. Hall (B.Soc.Sc.(SW), MB,Ch.B)
Last updated: 2008/05/19

 
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