Treatment guide: Severe Persistent Asthma (Adults)
Last updated: Monday, November 26, 2007
You have asthma symptoms every day, and
frequently during the night.
What is happening in your
lungs?
You have chronic inflammation in the inner
lining of the bronchioli, and this inflamed mucous membrane is swollen and red,
decreasing the diameter of the lumen of the bronchioli. The inflammation is
chronic and severe. Using only a bonchodilator is not enough. The bronchodilator
cannot reduce the inflammation. You need treatment to reduce the chronic
inflammation, probably due to an allergen or allergens. The only way to reduce
chronic inflammation is to treat it daily with an anti-inflammatory drug. In the
case of inflammation of the bronchioli,
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the best and most effective treatment is
corticosteroid (an anti-inflammatory) administered directly to the lungs by
inhaling it in aerosol form. In summary: You need to take your inhaled
corticosteroid every day (most probably twice a day, as prescribed by the
doctor).
The circular muscles around the bronchioli constrict
quite often in your case, probably triggered by some or other allergen or
event. This constriction can narrow the inner, already swollen, lumen of the
airways even more. This further narrowing will lead to asthma symptoms: your
chest can feel tight, you will feel as if it is difficult to breathe, and you may
have a dry, chesty cough. Whenever you feel these symptoms, you need to use your
short-acting bronchodilator inhaler. This medication will relax the constricted
circular muscle very soon and the whole muscle wall will relax, opening the
lumen again.
Your treatment
Your asthma is severe
and you need aggressive treatment:
You need a short-acting
bronchodilator (beta 2 blocker) maybe four to six times a day when your symptoms
worsen.
Your need increased dosages of inhaled corticosteroids to reduce
the severe inflammation.
You also need a long-acting bronchodilator to keep the muscles relaxed. Nowadays the corticosteroid and
long-acting beta2 blocker are combined in one inhaler.
You may even need
theophylline intravenously.
You may need oral corticosteroids for seven to 14
days to gain rapid control over the severe inflammation.
Helpful tips for an action
plan
Your doctor may hospitalise you.
Never go
without your short-acting bronchodilator inhaler. Use when you need
to.
Use your daily inhaled corticosteroid or combination inhaler
as prescrided.
Stay in contact with your doctor if you're
at home. Don't be on your own.
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