Over-the-counter drugs treat symptoms of flu, but not the cause. It will not cure flu, but will relief some symptoms. If the flu is not very severe, these, and vitamins and herbal remedies may be sufficient. These medications can make life more bearable during your illness.
As the flu is a viral infection, it will not respond to any antibiotic.
Antibiotics are only effective in treating secondary bacterial infections sometimes associated with influenza.