Pregnant women with epilepsy face a difficult decision: to continue treatment with anti-epileptic drugs and risk birth defects or stop taking the drugs and risk uncontrolled seizures that can harm the foetus, contends a report in the journal Epilepsia.
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90% give birth to healthy babies
The article, which reviewed recent data on the issue, noted that the consensus is that the use of drugs to treat epilepsy increases the risk for birth defects. But it also said most women with active epilepsy continue their drug therapy and that more than 90 percent of them give birth to healthy babies.
It's unclear whether the risk of birth defects varies with different anti-epileptic drugs. One drug, valproate, has been associated with a greater risk of birth defects compared with other epilepsy drugs, the article said, but the reason for this has not been clarified.
Possible postnatal effects
Pregnant women with epilepsy and their doctors also need to be concerned about possible postnatal effects of anti-epileptic drugs that may not become apparent until a child reaches school age, the article indicated.
"The risk of inducing harmful seizures by abrupt withdrawal of treatment is stressed and the importance of individual counselling is underlined," the authors noted. "The importance of maintained seizure control for the well-being of women with epilepsy, as well as for their unborn children, must be kept in mind." – (HealthDayNews)
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