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03 April 2012

Cheap, safe device helps avoid premature birth

A simple low-cost silicon ring can slash the risk of premature birth, a major cause of death in newborns and health problems in adult life, according to a trial by The Lancet.

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A simple low-cost silicon ring can slash the risk of premature birth, a major cause of death in newborns and health problems in adult life, according to a trial reported by The Lancet.

Spanish doctors tested the R305 device, known as a pessary, on women in their last three months of pregnancy who had cervical shortening, a condition that weakens the pelvic floor and leads to pre-term birth.

The pessary is designed to strengthen the cervix – the lower end of the uterus that leads to the vagina – so that it can cope with the extra weight of the final weeks of pregnancy.

Silicon pessaries have been used over the past 50 years as one of several methods to prevent pre-term births.

Safety debated

But their effectiveness has been debated, and this was the first time the device had been investigated in a randomised trial.

6% of women who were fitted with the pessary gave birth prematurely, compared to 27% of counterparts who did not have the device, according to the study.

The so-called PECEP trial recruited 15,000 women who underwent ultrasound examination in five hospitals when they were in between 20 and 23 weeks of pregnancy.

Of these, 380 had cervical shortening – defined as a having a cervix whose length was 25mm or less – and were randomly assigned to one of two groups, each comprising 190 women.

No side effect in peccary

In the pessary group, 12 had a baby before 34 weeks of pregnancy, while the number in the non-pessary group was 51.

No side effects were reported in the peccary group, and 95% of its participants said they would recommend the treatment for others.

"Placement of a pessary is an affordable procedure, non-invasive and easy to insert and remove as required," said lead researcher Maria Goya, an obstetrician at the Vall d'Hebron University Hospital in Barcelona.

(Sapa, April 2012) 

Read more:

Premature birth a precursor of problems

Infant and child mortality

 
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