Baptisia australis, Baptisia tinctoria (L.) R. B., Baptisia tinctoria (L.) R. Br., Baptisiae tinctoriae radix, blue false indigo, blue wild indigo, Fabaceae (family), horse fly weed, indigo carmine, indigo weed, rattlebush, rattleweed, wild indigo root.
Wild indigo (Baptisia australis) has deep blue to violet flowers, similar to sweet pea flowers. When the plant's sap is exposed to air, it turns purple. Although this sap has been used for dying, it is not as colorfast as true indigo (Indigofera tinctoria). Some Native Americans tribes used a tea of blue indigo root as an emetic (induces vomit) and purgative.
Wild indigo is considered toxic and is on the U. S. Food and Drug Administration's (FDA) list of toxic plants. However, two studies in humans found no adverse effects when it was used in a combination of Baptisiae tinctoriae radix, Echinaceae pallidae/purpureae radix, and Thujae occidentalis herba. Currently, wild indigo seems most promising as an immunomodulator, as both laboratory studies and clinical studies using combination products have noted some benefit. However, more studies are needed using wild indigo as a monotherapy before its safety and efficacy can be determined.
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Respiratory tract infections
Preliminary evidence has shown immunostimulative properties in wild indigo extracts. However, the available clinical studies have been conducted using the combination called Esberitox N (Echinaceae (purpureae et pallidae) radix, Baptisiae tinctoriae radix and Thujae occidentalis herba). Additional study is needed using wild indigo alone to determine effectiveness for respiratory tract infections.
*Key to grades:
A: Strong scientific evidence for this use;
B: Good scientific evidence for this use;
C: Unclear scientific evidence for this use;
D: Fair scientific evidence against this use (it may not work);
F: Strong scientific evidence against this use (it likely does not work).
The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below. Antiviral, emetic (induces vomiting), immunomodulation, laxative (purgative).
The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.
Adults (18 years and older):
There is no proven safe or effective dose for wild indigo in adults. Wild indigo is considered toxic and is on the U. S. Food and Drug Administration's (FDA's) list of toxic plants.
Children (younger than 18 years):
There is no proven safe or effective dose for wild indigo in children. Wild indigo is considered toxic and is on the U. S. Food and Drug Administration's (FDA's) list of toxic plants.
The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.
Avoid in individuals with a known allergy or hypersensitivity to wild indigo (Baptisia australis) or its constituents.
Side Effects and Warnings
There is little information available on the adverse effects of wild indigo in the literature. However, when used in a combination of Baptisiae tinctoriae radix, Echinaceae pallidae/purpureae radix, and Thujae occidentalis herba, two studies in humans found no adverse effects. Wild indigo is considered toxic and is on the U. S. Food and Drug Administration's (FDA's) list of toxic plants. Use cautiously in patients on immunosuppressive therapy as wild indigo may be an immunostimulator or immunomodulator.
Pregnancy and Breastfeeding
Wild indigo is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence.
Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.
Interactions with Drugs
The combination of an herbal preparation comprised of Echinacea, wild indigo and white cedar mat have antiviral characteristics. Caution is advised when taking wild indigo with other antiviral agents.
Preliminary evidence suggests that wild indigo may have immunostimulative or immunomodulating effects. Use cautiously with other immunosuppressive agents.
Interactions with Herbs and Dietary Supplements
The combination of an herbal preparation comprised of Echinacea, wild indigo and white cedar mat have antiviral characteristics. Caution is advised when taking wild indigo with other antiviral herbs or supplants.
Preliminary evidence suggests that wild indigo may have immunostimulative or immunomodulating effects. Use cautiously with other immunosuppressive herbs or supplements.
This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).
Natural Standard Bottom Line Monograph, Copyright © 2011 (www.naturalstandard.com). Commercial distribution prohibited. This monograph is intended for informational purposes only, and should not be interpreted as specific medical advice. You should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.
While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy.
The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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Copyright © 2011 Natural Standard (www.naturalstandard.com)
Copyright © 2011 Natural Standard (www.naturalstandard.com)