Meds and you

27 September 2013

Terbinafine

Terbinafine is an antimycotic. Antimycotics are drugs that destroy or prevent the growth of fungi. An antimycotic drug is therefore an antifungal drug.

0

Terbinafine is the active ingredient of Dermax (Nappi Code: 707299-001), Lamisil Tabs (Nappi Code: 842087-001 & , 792713-001), Merck-Terbinafine (Nappi Code: 705114-001), Nafin 250 (Nappi Code: 706553-001), Terbane (Nappi Code: 706757-001), Terbicil (Nappi Code: 705430-001), Lamisil cream (Nappi Code: 792705-017/009), Lamisil spray (Nappi Code: 703033-001 & 836486-005), Lamisil Dermgel (Nappi Code: 880892-005), Terbicil Cream (Nappi Code: 706073- and 001/002).

General information
Terbinafine is an antimycotic. Antimycotics are drugs that destroy or prevent the growth of fungi. An antimycotic drug is therefore an antifungal drug.

In South Africa terbinafine is registered for the treatment of infections of skin, hair and nails due to susceptible fungal infection.

Terbinafine is available as an oral drug, or in the form of various topical applications.

Some patients may experience a loss of taste when the oral form of this drug is taken. This recovers within a few weeks.

Treatment with terbinafine should only be stopped once the prescribed course has been completed, or if your doctor instructs you to do so.

This medication is only effective in treating fungal infections and will not be effective for treating bacterial or viral infections.

How does terbinafine work?
Terbinafine disrupts the stability of fungal cell membranes and causes the formation of holes within this membrane.

Fast facts

Drug schedule: schedule 4
Available as: terbinafine is available as tablets, cream, spray and gel.
What does it do? Terbinafine destroys or prevents the growth of fungi.
Overdose risk: low
Dependence risk: low
Is terbinafine available as a generic? yes
Is terbinafine available on prescription only? yes

User information

Onset of effect: an adequate response may require months of treatment.
Duration of action: up to 24 hours
Stopping this medicine: do not stop taking terbinafine without consulting your doctor. If you stop taking this medicine too soon, your symptoms may return.

Special precautions
Consult your doctor before using this drug if:

 

  • you have a liver disease
  • you have porphyria
  • you have psoriasis

Pregnancy: avoid. Potential risk to the foetus has been reported. Consult your doctor before use, or if you are planning to fall pregnant.
Breastfeeding: avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.
Porphyria: avoid. This medication may cause serious adverse effects. Consult your doctor before use.
Infants and children: this medication is not intended for use in children younger than 2
The elderly: caution is advised for the elderly.
Driving and hazardous work: caution is advised as use of this medication may lead to dizziness, light-headedness and/or sedation. Avoid such activities until you know how this medication affects you.
Alcohol: avoid concomitant use of alcohol with this medication.

Possible side effects

 

Side Effect
Frequency
Consult your doctor
 
Common
Rare
Only if severe
In all cases
diarrhoea
X
 
X
 
nausea
X
 
X
 
loss of appetite
X
 
X
 
abdominal pain
X
 
X
 
mild skin rash
X
 
X
 
metallic taste in mouth
 
X
X
 
loss of taste
 
X
X
 
discolouration of tongue
 
X
X
 
severe rash
 
X
 
X
hair loss
 
X
X
 
yellowing of the skin or eyes
 
X
 
X
unusually dark urine
 
X
 
X

Interactions

alcohol increased risk of liver damage
cimetidine increased risk of terbinafine toxicity
oral contraceptives efficacy of pill may be affected
rifampicin efficacy of terbinafine may be lowered

Disease interactions
Consult your doctor before using this drug if you have a liver disease, psoriasis or if you have porphyria.

Overdose action
A small overdose is no cause for concern. In case of intentional large overdose seek emergency medical attention.

Recommended dosage
Adult: oral, 125mg twice daily or 250 mg once a day

 

This material is not intended to substitute medical advice, but is for informational purposes only. Please consult a physician for specific treatment and recommendations.
 
 

Read Health24’s Comments Policy

Comment on this story
0 comments
Comments have been closed for this article.