Meds and you

30 September 2013

Prednisolone and cinchocaine

The combination of prednisolone and cinchocaine has an anti-haemorrhoidal effect.


The combination of prednisolone and cinchocaine is the active ingredient of Scheriproct ointment (Nappi code: 762660-007, 015) & Scheriproct suppositories (Nappi code: 875384-005).

General information
The combination of prednisolone and cinchocaine has an anti-haemorrhoidal effect. Anti-haemorrhoidals are drugs that relieve and reduce the symptoms of haemorrhoids, a condition associated with swelling and inflammation of veins in the rectum and anus.

In South Africa this combination is registered for the treatment of short-term symptomatic relief of haemorrhoids, anal fissure (a small tear in the anus), and anal itching.

This medication does not cure the underlying condition, but simply keeps the symptoms under control. For it to be effective, it has to be taken regularly. Straining during defecation should furthermore best be avoided.

It is advised not to continue treatment for longer than 7 days to prevent systemic side effects associated with both active ingredients found in this product.

How does this combination work?
Cinchocaine numbs the area where the medication has been applied, relieving pain and itching, while prednisolone - a corticosteroid - reduces inflammation, swelling and irritation.

Fast facts
Available as: this combination is available as both suppositories and as an ointment.
What does it do? This combination relieves the symptoms associated with haemorrhoids, and related skin conditions in the anal and rectal region.
Overdose risk: medium
Dependence risk: low
Is this combination available as a generic? no
Is this combination available on prescription only? yes

User information
Stopping this medicine: complete the course as directed by your doctor.
Prolonged use: this product is not intended for long-term use.

Special precautions
Consult your doctor before using this drug if:

  • you have an untreated viral, fungal or secondary bacterial in the affected area
  • you are allergic to local anaesthetics
  • you are experiencing rectal bleeding
  • you are pregnant

Pregnancy: avoid. Potential risk to the foetus has been reported. Consult your doctor before use, or if you are planning to fall pregnant.
avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.
Porphyria: avoid. It is unknown how this medication may affect your condition. Consult your doctor before use.
Infants and children: this medication is not intended for use in children.
The elderly: no special precautions need to be taken.

Possible side effects

Side Effect
Consult your doctor

Only if severe
In all cases
thinning of the skin in the anal region


allergic reactions




Drug interactions

Interactions are not expected at the prescribed dosage and duration of treatment.

Overdose action
A small overdose is no cause for concern. In case of intentional large overdose, seek emergency medical attention.

Recommended dosage
Adults, suppositories :insert one suppository per rectum daily. Ointment: clean the affected area and apply twice daily as needed.


This material is not intended to substitute medical advice, but is for informational purposes only. Please consult a physician for specific treatment and recommendations.


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