Meds and you

27 September 2013

Niclosamide

Niclosamide is an antihelmintic drug. Antihelmintic drugs are drugs that are used in the treatment of worm infestations.

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Niclosamide is the active ingredient of Yomesan (Nappi code: 778877-019/027).

General information
Niclosamide is an antihelmintic drug. Antihelmintic drugs are drugs that are used in the treatment of worm infestations. In South Africa niclosamide is registered for the treatment of tapeworm infections.

If a patient is constipated prior to treatment, a purgative is necessary on the night before treatment. A purgative is once again advised 2 hours after dosing.

No alcohol should be taken during treatment with niclosamide.

How does niclosamide work?
Niclosamide blocks certain metabolic processes of the susceptible worm species, resulting in the death of worms in various phases of development.

Fast facts

Drug schedule: schedule 0
Available as: niclosamide is available as tablets.
What does it do? Niclosamide is used in the treatment of worm infestations.
Overdose risk: low
Dependence risk: low
Is Niclosamide available as a generic? no
Is Niclosamide available on prescription only? no

User information
Special precautions

Pregnancy: avoid. It is unknown how this medication may affect your baby. Consult your doctor before using this drug, or if you are planning to fall pregnant.
Breastfeeding: avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.
Porphyria: avoid. It is unknown how this medication may affect your condition. Consult your doctor before use.
Infants and children: this medication is not intended for use in children under the age of 2.
The elderly: no special precautions need to be taken.
Driving and hazardous work: caution is advised as use of this medication may lead to dizziness, light-headedness and/or sedation. Avoid such activities until you know how this medication affects you.
Alcohol: avoid concomitant use of alcohol with this medication.

Possible side effects

Side Effect
Frequency
Consult your doctor

Common
Rare
Only if severe
In all cases
diarrhoea

X
X

nausea / vomiting

X
X

light-headedness

X
X

skin rash/itch

X

X

Interactions

alcohol increases niclosamide side-effects

Overdose action
A small overdose is no cause for concern. In case of intentional large overdose seek emergency medical attention.

Recommended dosage
Adults:
Tapeworm: 2 g as a single dose

This material is not intended to substitute medical advice, but is for informational purposes only. Please consult a physician for specific treatment and recommendations.
 
 

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