Meds and you

27 September 2013

N-acetylcysteine for injection

N-acetylcysteine is a mucolytic. In the injectable form it is however used as a poison antidote.

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(Also known as acetylcysteine)

N-acetylcysteine is the active ingredient of Parvolex injection (Nappi code: 788740-008).

General information
N-acetylcysteine is a mucolytic. In the injectable form it is however used as a poison antidote.

In South Africa N-acetylcysteine in the injectable form is registered as an antidote in paracetamol overdose.

Treatment should be started within 15 hours of overdose in order to be effective.

How does N-acetylcysteine work?
This medication works protect the liver from damage following paracetamol overdosage.

Fast facts

Drug schedule: schedule 2
Available as: N-acetylcysteine is available as Eefervescent tablets, granules and lozenges.
What does it do? N-acetylcysteine protects the liver from damage following paracetamol overdosage
Overdose risk: low
Dependence risk: low
Is N-acetylcysteine available as a generic? no
Is N-acetylcysteine available on prescription only? no

Special precautions
Consult your doctor before using this drug if:

Pregnancy: avoid. It is unknown how this medication may affect your baby. Consult your doctor before using this drug, or if you are planning to fall pregnant.
Breastfeeding: avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.
Porphyria: this medication is safe for use.
Infants and children: this medication is not intended for use in children under the age of two years.
The elderly: this medication should only be administered by a specialist.

Possible side effects

Side Effect
Frequency
Consult your doctor

Common
Rare
Only if severe
In all cases
palpitations

X

X
skin reactions or more severe allergic reactions

X

X

Interactions

Drug interactions

nitroglycerine may increase lowering of blood pressure

This material is not intended to substitute medical advice, but is for informational purposes only. Please consult a physician for specific treatment and recommendations.

 
 

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