(Also known as sulfiram, tetraethylthiuram monosulphide)
Monosulfiram is the active ingredient of Tetmosol (Nappi Code:
Monosulfiram is an ectoparasiticide.
Ectoparasiticides are drugs that are used to treat ectoparasitic infections.
Ectoparasites - parasites found on the surface of the body - include scabies,
a skin disorder caused by a mite that burrows into the skin and produces an
intense, itchy rash, and pediculosis, better known as a lice infection with
either the head, pubic or body louse.
In South Africa monosulfiram is registered for the prevention and treatment
It is especially useful in controlling scabies outbreaks in boarding schools,
hospitals and other closed communities.
If systemically absorbed, this product may react adversely with alcohol,
causing nausea, vomiting and headache. Abstain from using alcohol for 48 hours
before and after application.
How does monosulfiram work?
Monosulfiram have been shown to readily
kill the scabies mite, sarcoptes scabiei.
Drug schedule: unscheduled
Available as: this medication is
available as an emulsion.
What does it do? Monosulfiram kills
Overdose risk: low
Dependence risk: low
monosulfiram available as a generic? yes
Is monosulfiram available on
prescription only? no
Consult your doctor before using this drug
- you have sensitive skin
- you have had previous allergic reactions with this product
- you are pregnant or breastfeeding
Pregnancy: avoid. It is unknown how this medication may affect your
baby. Consult your doctor before using this drug, or if you are planning to fall
Breastfeeding: avoid. It is unknown how this medication may
affect your baby. Consult your doctor before use.
Porphyria: avoid. It
is unknown how this medication may affect your condition. Consult your doctor
Infants and children: no special precautions need to be
The elderly: no special precautions need to be
Driving and hazardous work: no special precautions need to be
Alcohol: abstain from using alcohol before and for at least 48
hours after the application of this soap.
Possible side effects
Consult your doctor
Only if severe
In all cases
|nausea/vomiting when taking alcohol
No interactions are known.
Consult your doctor before using this drug if
you are pregnant or breastfeeding.
A small overdose is no cause for concern. If
ingested, seek emergency medical attention.
Monosulfiram is used in place of ordinary toilet
soap. Ideally, the person should bathe in hot water and soap themselves
liberally with the soap paying particular attention to the folded areas of the
skin. After bathing, the body should be allowed to dry naturally or dried with a
towel using a 'blotting' action. The soap should be used daily for as long as
the danger of infection remains.
This material is not intended to substitute medical advice, but is
for informational purposes only. Please consult a physician for specific
treatment and recommendations.