Meds and you

27 September 2013

Methylprednisolone

Methylprednisolone is a topical corticosteroid. Topical corticosteroids are steroid medications that that are formulated for use on the skin.

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Methylprednisolone is the active ingredient of Advantan cream (Nappi code: 793108-020/039), Advantan ointment (Nappi code: 793086-035/043), Advantan fatty ointment (Nappi code: 793116-023/031), Advantan milk (Nappi code: 883180-006) and Advantan scalp solution (Nappi code: 701417-001).

General information

Methylprednisolone is a topical corticosteroid. Topical corticosteroids are steroid medications that that are formulated for use on the skin. They reduce inflammation and are effective for treating inflammatory skin conditions.

In South Africa methylprednisolone is registered for the treatment of non-infected steroid responsive diseases and disorders affecting the skin.

This medication should be applied sparingly and as a thin, even layer to the affected area of the skin. Do not apply to broken skin, or apply more than directed.

Prolonged use on large surface areas, application of large amounts, or covering the application site with dressings, may increase systemic absorption, resulting in a decrease in the production of natural hormones by the adrenal glands. Prolonged or excessive use of this medicine may lead

to thinning of the skin.

Do not apply to the face and avoid contact with the eyes.

Speak to your doctor before applying this medicine to infected skin.

How does methylprednisolone work?

When applied to the skin, methylprednisolone reduces the release of inflammatory chemicals. This reduces inflammation and its associated symptoms.

Fast facts

Drug schedule: schedule 4

Available as: methylprednisolone is available as cream, ointment, fatty ointment, milk and scalp lotion.

What does it do? Methylprednisolone relieves inflammation of the skin.

Overdose risk: low

Dependence risk: low

Is methylprednisolone available as a generic? no

Is methylprednisolone available on prescription only? no and yes

User information

Stopping this medicine: do not stop using this medication abruptly as it may cause a recurrence of the original symptoms being treated. Consult with your doctor prior to discontinuing treatment.

Prolonged use: this medicine is not intended for long-term use as this may lead to permanent skin changes. Duration of treatment should generally not exceed four weeks.

Special precautions

Consult your doctor before using this drug if:

- you have a bacterial, fungal or viral skin infection

- you have porphyria

- you have skin ulcers/broken skin

- you have acne or rosacea

Pregnancy: avoid. It is unknown how this medication may affect your baby. Consult your doctor before using this drug, or if you are planning to fall pregnant.

Breastfeeding: avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.

Porphyria: avoid. This medication may cause serious adverse effects. Consult your doctor before use.

Infants and children: avoid. No data available for use in children.

The elderly: no special precautions need to be taken.

Driving and hazardous work: no special precautions need to be taken.

Alcohol: no special precautions need to be taken.

Possible side effects

Side effects Frequency
Consult your doctor

Common Rare Only if severe In all cases
Burning x
x
Itching x
x
Skin thinning
x
x
Skin infections
x
x
systemic effects
x
x

Interactions

Drug interactions

Interactions are uncommon when this medication is used as directed.

Overdose action

A small overdose is no cause for concern. In case of intentional large overdose, seek emergency medical attention.

Recommended dosage

Apply sparingly to the affected area once daily.

This material is not intended to substitute medical advice, but is for informational purposes only.

Please consult a physician for specific treatment and recommendations.

 
 

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