Meds and you

27 September 2013

Mesna

Mesna is the active ingredient of Mistabrion nasal spray.

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Mesna
(Also known as sodium 2-mercaptoethanesulphonate)

Mesna is the active ingredient of Mistabrion nasal spray (Nappi Code: 743976-002).

General information
Mesna is a mucolytic. Mucolytics are drugs that dissolve or break down mucus. This reduces the thickness of mucus and phlegm.

In South Africa mesna is registered for the treatment of nasal obstruction due to too thick nasal secretions and also for the treatment of rhinitis.

This medication does not cure the underlying condition, but simply keeps the symptoms under control. For it to be effective, it has to be taken regularly, even if you do not notice an immediate effect.

How does mesna work?
This medication works by breaking some of the chemical bonds between the molecules in mucus. This makes secretions less thick and sticky.

Fast facts
Drug schedule: schedule 2
Available as: mesna is available as nasal spray
What does it do? Mesna dissolves or breaks down mucus.
Overdose risk: low
Dependence risk: low
Is mesna available as a generic? no
Is mesna available on prescription only? no

User information
Stopping this medicine: treatment with this medication can be safely stopped when no longer needed.

Special precautions
Consult your doctor before using this drug if:

- you have asthma
- you have been diagnosed with a condition called atrophic rhinitis

Pregnancy: Not known to be harmful. Consult your doctor before using this drug, or if you are planning to fall pregnant.
Breastfeeding: avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.
Porphyria: avoid. It is unknown how this medication may affect your condition. Consult your doctor before use.
The elderly: no special precautions need to be taken.

Possible side effects

Side effect

Frequency

Consult your doctor

Common

Rare

Only if severe

In all cases

nausea/vomiting


x

x


diarrhoea


x

x


headache


x

x


bad taste in mouth


x

x


severe cough or respiratory distress


x


x

skin reactions – allergic


x


x

Interactions

Drug interactions

No known interactions.

Overdose action
A small overdose is no cause for concern. In case of intentional large overdose, seek emergency medical attention.

Recommended dosage
Adults, intranasal: one spray in each nostril 4-6 times daily.


This material is not intended to substitute medical advice, but is for informational purposes only.
Please consult a physician for specific treatment and recommendations.

 
 

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