Meds and you

27 September 2013

Mebeverine

Mebeverine is an anti-spasmodic. Anti-spasmodics are agents that relieve smooth muscle spasms or cramps.

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Mebeverine is the active ingredient of Bevispas (Nappi Code: 822019-019), Colofac (Nappi Code: 715476-009/017), Merck-Mebeverine HCL (Nappi Code: 7701892-003/006) and Sandoz Mebeverine HCL (Nappi Code: 825328-004).

General information
Mebeverine is an anti-spasmodic. Anti-spasmodics are agents that relieve smooth muscle spasms or cramps.

In South Africa mebeverine is registered for the treatment of irritable bowel syndrome, a condition in which the colon muscle contracts more readily, causing abdominal pain and cramps, excess gas, bloating and a change in bowel habits; abdominal pain and abdominal discomfort, pain and bloating experience after meals.

Mebeverine does not cure the underlying condition, but simply keeps the symptoms under control. It should be noted that, for mebeverine to be effective, it has to be taken regularly.

How does mebeverine work?
Mebeverine relaxes the muscles in the walls of the bowel and also prevents further spasms in these muscles by reducing nerve transmission to them.

Fast facts

Drug schedule: schedule 2
Available as: mebeverine is available as tablets.
What does it do? Mebeverine relieves gastro-intestinal muscle spasms.
Overdose risk: low
Dependence risk: low
Is Mebeverine available as a generic? yes
Is Mebeverine available on prescription only? no

User information

Onset of effect: within 60 minutes
Duration of action: up to 8 hours
Stopping this medicine: mebeverine can be safely stopped when no longer needed.

Special precautions
Consult your doctor before using this drug if:

  • you have liver or kidney disease

  • you have heart disease

  • you have porphyria

Pregnancy: avoid. It is unknown how this medication may affect your baby. Consult your doctor before using this drug, or if you are planning to fall pregnant.
Breastfeeding: avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.
Porphyria: avoid. This medication may cause serious adverse effects. Consult your doctor before use.
Infants and children: this medication is not intended for use in children under the age of 10 years
The elderly: no special precautions need to be taken.
Driving and hazardous work: caution is advised as use of this medication may lead to dizziness, light-headedness and/or sedation. Avoid such activities until you know how this medication affects you.
Alcohol: no special precautions need to be taken.

Possible side effects

Side Effect
Frequency
Consult your doctor

Common
Rare
Only if severe
In all cases
constipation
X

X

diarrhoea

X
X

nausea/vomiting

X
X

loss of appetite

X
X

headache

X
X

dizziness

X
X

insomnia

X
X

depression

X

X
agitation

X

X
confusion

X

X

Interactions
No known drug interactions

Disease interactions
Consult your doctor before using this drug if you have liver or kidney disease, heart disease, or if you have porphyria.

Overdose action
A small overdose is no cause for concern. In case of intentional large overdose seek emergency medical attention.

Recommended dosage
Adults: oral, 135 mg 1-3 times daily

This material is not intended to substitute medical advice, but is for informational purposes only. Please consult a physician for specific treatment and recommendations.
 
 

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