Meds and you

Updated 11 February 2013


Loracarbef is a broad-spectrum antibiotic, which is effective in treating a variety of bacterial infections.


Loracarbef is the active ingredient of Lorabid.

General information

Loracarbef is a broad-spectrum antibiotic, which is effective in treating a variety of bacterial infections. It is frequently prescribed to treat mild to moderate upper and lower respiratory tract infections such as pneumonia, bronchitis, pharyngitis and tonsillitis, middle-ear infections, skin and soft-tissue infections and uncomplicated urinary tract infections cause by organisms that are susceptible to loracarbef.

It is important to note that this medication is only effective against bacterial infections - if your infection is the result of a viral or fungal infection, it will be ineffective.

Antibiotic resistance (that is, when bacteria develop the ability to defend themselves against the effect of an antibiotic) occurs frequently with many antibiotics. This most often occurs when patients do not complete the prescribed course in full or when antibiotics are used for non-bacterial infections such as cold and flu.

Persons who are allergic to penicillin should take loracarbef with caution. Although it is not a penicillin, cross-sensitivity (which means that you may also be allergic to this drug) may occur.

How does loracarbef work?

Loracarbef weakens the bacterial cell wall and allows water to enter the cell, causing cells to burst.

Fast facts

Drug schedule: schedule 4

Available as: loracarbef is available as capsules and suspension

What does it do? this medication has an antibiotic action

Overdose risk: low

Dependence risk: low

Is loracarbef available as a generic? no

Is loracarbef available on prescription only? yes

User information

Onset of effect: may take a few days for the full beneficial effect to be reached

Duration of action: up to 12 hours

Dietary advice: this medication should best be given on an empty stomach

Stopping this medicine: do not stop taking this medication until you have finished the course as prescribed by your doctor - infection may recur with premature discontinuation

Prolonged use: loracarbef is usually given only for short courses of treatment

Special precautions

Consult your doctor before using this drug if:

  • you have kidney disease
  • you are allergic to other cephalosporins or penicillin
  • you are taking other medication

Pregnancy: avoid. It is not known how this medication may affect your baby. Consult your doctor before using this drug, or if you are planning to fall pregnant.

Breastfeeding: avoid. This medication is passed through breast milk and may affect your baby adversely. Consult your doctor before use.

Porphyria: avoid. This medication may cause serious adverse effects. Consult your doctor before use.

Infants and children: this medication is safe for use in children at the recommended dose.

Elderly: caution is advised in the elderly as adverse effects may be more severe.

Driving and hazardous work: caution is advised as use of this medication may lead to dizziness. Avoid such activities until you know how this medication affects you.

Alcohol: avoid concomitant use of alcohol with this medication.

Possible side effects

Side effect


Consult your doctor



Only if severe

In all cases




stomach cramps



nausea and vomiting



rash/ hives/ itchy skin



dizziness/ light-headedness






breathing difficulties



swelling of face/ throat




Drug interactions


increased risk of warfarin toxicity

non-steroidal anti-inflammatory drugs

increased risk of bleeding


drugs may counteract each other

vancomycin/ aminoglycoside antibiotics

increased risk of kidney toxicity

oral contraceptives

risk of contraceptive failure


increased levels of antibiotic in body

Overdose action

A small overdose is no cause for concern. In case of intentional large overdose, seek emergency medical attention. Symptoms may include seizures, severe abdominal pain and vomiting.

Recommended dosage

Adults: 400-800mg daily, divided in two doses

Children: 8-16mg/kg, divided in two doses (max 400mg/dose)

This material is not intended to substitute medical advice, but is for informational purposes only. Please consult a physician for specific treatment and recommendations.


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