Meds and you

27 September 2013

Lindane

Lindane is an ectoparasiticide. Ectoparasiticides are drugs that are used to treat ectoparasitic infections.

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(Also known as Gamma-benzenehexachloride)

Lindane is the active ingredient of Gambex (Nappi Code: 727881-051).

General Information
Lindane is an ectoparasiticide. Ectoparasiticides are drugs that are used to treat ectoparasitic infections.

Ectoparasitic - parasites found on the surface of the body - include scabies, a skin disorder caused by a mite that burrows into the skin, and produces an intense, itchy rash, and pediculosis, better known as a lice infection with either the head, pubic or body louse.

In South Africa lindane is registered for the treatment of head, body and pubic lice infections. It is also effective in treating scabies, but due to its toxicity safer alternatives are preferred.

Lindane should only be applied as directed and repeated exposure should be avoided.

Contact with broken skin, mucous membranes and the eyes should be avoided.

How does lindane work?
Lindane is a nerve poison that causes paralysis and death of parasites as a result of its effect on the parasitic nervous system.

Fast facts

Drug schedule: schedule 0
Available as: this medication is available as a shampoo
What does it do? Lindane kills parasites.
Overdose risk: medium
Dependence risk: low
Is lindane available as a generic? no
Is lindane available on prescription only? no

User information

Prolonged use: due to toxicity this chemical is not intended for prolonged use.

Special precautions
Consult your doctor before using this drug if:

  • you have epilepsy

  • you have sensitive skin

  • you are pregnant or breastfeeding

Pregnancy: avoid. It is unknown how this medication may affect your baby. Consult your doctor before using this drug, or if you are planning to fall pregnant.
Breastfeeding: avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.
Porphyria:avoid. It is unknown how this medication may affect your condition. Consult your doctor before use.
Infants and children: this medication is not intended for use in children under one year of age.
Elderly: caution is advised in the elderly as they may be more susceptible to adverse effects.
Driving and hazardous work: no special precautions need to be taken.
Alcohol: no special precautions need to be taken.

Possible side effects

Side Effect

Frequency
Consult your doctor

Common
Rare
Only if severe
In all cases

itching

X
X

stinging

X
X

rash

X
X

irritability

X

muscle cramps

X

convulsions

X

headache

X

nausea/vomiting

X

Interactions
No interactions are known.

Disease interactions
Consult your doctor before using this drug if you have epilepsy.

Overdose action
A small overdose is no cause for concern. If accidentally swallowed, seek emergency medical attention.

Recommended dosage
Apply 30 ml to the affected parts and rub for a few minutes. Rinse off and repeat after 24 hours if necessary.

For scabies and body lice the lotion should be applied to the whole body (excluding the head and neck) and the lindane should be left on for 12-24 hours.

For head lice the hair should be washed with the shampoo and it should be left on for at least 4 minutes. It is advised that the hair be combed with a nit comb afterwards.

This material is not intended to substitute medical advice, but is for informational purposes only. Please consult a physician for specific treatment and recommendations.
 
 

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