Levobunolol is the active ingredient of Betagan ophthalmic solution (Nappi
Levobunolol is a beta-receptor blocker.
Beta-receptor blockers are drugs that act on beta-receptors in the heart,
thereby reducing its force and speed of contraction, and on blood vessels,
preventing vasodilatation. In the form of eye drops, beta-receptor blockers are
used to reduce fluid pressure within the eye.
In South Africa levobunolol is registered for the control of intra-ocular
pressure in chronic open-angle-glaucoma and in ocular hypertension.
For this medication to be effective, it has to be taken regularly, even if
you do not notice an immediate effect.
It should be noted that because this drug may cause dizziness,
light-headedness and/or visual disturbances, driving and any hazardous tasks
should be avoided until you know how this medication affects you.
Levobunolol ophthalmic drops should not be used if you have soft contact
lenses in your eyes.
How does levobunolol work?
Levobunolol as an eye drop causes blood
vessels in the eye to narrow. By narrowing these blood vessels, less fluid
passes through the blood vessel into the eyeball, thereby reducing pressure
within the eye. It furthermore reduces the production of aqueous humour within
Drug schedule: schedule 3
Available as: levobunolol is
available as eye drops.
What does it do? Levobunolol reduces pressure
inside the eyes.
Overdose risk:v medium
Is levobunolol available as a generic? no
available on prescription only? yes
Stopping this medicine: do not stop taking this drug without
consulting your doctor.
Prolonged use: regular ophthalmic examination
is advised with long-term use. A decreased effect of this medication may
furthermore be noted with prolonged use.
Consult your doctor before using this
- you have or had heart disease
- you have asthma
- you have chronic bronchitis
- you have diabetes
- you have a slow heart rate (<50 beats per minute)
Pregnancy: avoid. Potential risk to the foetus has been reported.
Consult your doctor before use, or if you are planning to fall
Breastfeeding: avoid. This medication is passed through
breast milk and may affect your baby adversely. Consult your doctor before
Porphyria: avoid. It is unknown how this medication may affect
your condition. Consult your doctor before use.
Infants and children:
avoid as safety in children has not been established.
caution is advised in the elderly as side effects are more likely to
Alcohol: no special precautions need to be taken.
Possible side effects
Although this is an eye drop, systemic effects cannot be excluded and
these may include low blood pressure, a slow heart rate, heart rhythm
disturbances, congestive heart failure, chest pain, palpitations, difficulty
breathing, coughing, muscle weakness, cold hand and feet, headache and even
||lowering of blood pressure, slow heart rate and dizziness may occur
||increased side effects of digoxin |
||increased side effects of verapamil |
|oral beta-receptor blockers
||increased risk of side effects with both drugs
Consult your doctor before using this drug
if you have or had heart disease, you have asthma, chronic bronchitis, diabetes
or if you have a slow heart rate (<50 beats per minute).
A small overdose is no cause for concern. In
case of intentional large overdose, seek emergency medical attention.
Adults: 1 drop twice daily
This material is not intended to substitute medical advice, but is
for informational purposes only. Please consult a physician for specific
treatment and recommendations.