Fluocinolone is the active ingredient of Cortoderm cream (Nappi code:
716278-006), Cortoderm cream (Nappi code: 716278-014), Cortoderm ointment (Nappi
code: 716286-009), Cortoderm ointment (Nappi code: 716286-017), Synalar cream
(Nappi code: 768278-007), Synalar ointment (Nappi code: 768286-018) and Synalar
gel (Nappi code: 768294-002).
Fluocinolone is a topical corticosteroid. Topical corticosteroids are steroid
medicines that are formulated for use on the skin. They reduce inflammation and
are effective for treating inflammatory skin conditions.
In South Africa fluocinolone is registered for the treatment of non-infected
steroid responsive diseases and disorders affecting the skin.
This medication should be applied sparingly and as a thin, even layer to the
affected area of the skin. Do not apply to broken skin, or apply more than
Prolonged use on large surface areas, application of large amounts, or
covering the application site with dressings may increase systemic absorption,
resulting in a decrease in the production of natural hormones by the adrenal
glands. Prolonged or excessive use of this medicine may lead to thinning of the
Avoid contact with the eyes and do not apply to skin crease or ano-genital
areas and nappy areas of infants. If applied to the face, use for short periods
Speak to your doctor before applying this medicine to infected skin.
How does fluocinolone work?
When applied to the skin, fluocinolone reduces the release of inflammatory
chemicals. This reduces inflammation and its associated symptoms.
Drug schedule: schedule 4
Available as: fluocinolone is available as cream, ointment and
What does it do? Fluocinolone relieves inflammation of the skin.
Overdose risk: low
Dependence risk: low
Is fluocinolone available as a generic? yes
Is fluocinolone available on prescription only? yes
Stopping this medicine: do not stop using this medication abruptly as
it may cause a recurrence of the original symptoms being treated. Consult with
your doctor prior to discontinuing treatment.
Prolonged use: this medicine is not intended for long-term use as this
may lead to permanent skin changes. Safety of use for more than 5 days has not
Consult your doctor before using this drug if:
- you have a bacterial, fungal or viral skin infection
- you have porphyria
- you have skin ulcers/broken skin
- you have acne or rosacea
Pregnancy: avoid. It is unknown how this medication may affect your
baby. Consult your doctor before using this drug, or if you are planning to fall
Breastfeeding: avoid. It is unknown how this medication may affect
your baby. Consult your doctor before use.
Porphyria: avoid. This medication may cause serious adverse effects.
Consult your doctor before use.
Infants and children: this medication is not intended for use in
children under the age of 1 year.
The elderly: no special precautions need to be taken.
Driving and hazardous work: no special precautions need to be
Alcohol: no special precautions need to be taken.
Possible side effects
||Consult your doctor
||Only if severe
||In all cases|
Interactions are uncommon when this medication is used as directed.
A small overdose is no cause for concern. In case of intentional large
overdose, seek emergency medical attention.
Apply sparingly to the affected area 2 - 3 times daily.
This material is not intended to substitute medical advice, but is for
informational purposes only.
Please consult a physician for specific treatment and