Desonide is the active ingredient of Locatop cream (Nappi code:
Desonide is a topical corticosteroid. Topical corticosteroids are drugs that
are formulated for use on the skin. They reduce inflammation and are effective
for treating inflammatory skin conditions.
In South Africa desonide is registered for the treatment of non-infected
steroid responsive diseases and disorders affecting the skin.
This medication should be applied sparingly and as a thin, even layer to the
affected area of the skin. Do not apply to broken skin, or apply more than
Prolonged use on large surface areas, application of large amounts, or
covering the application site with dressings may increase systemic absorption,
resulting in a decrease in the production of natural hormones by the adrenal
glands. Prolonged or excessive use of this medicine may lead to thinning of the
Speak to your doctor before applying this medicine to the face or to infected
How does desonide work?
When applied to the skin, desonide reduces the release of inflammatory
chemicals. This reduces inflammation and its associated symptoms.
Drug schedule: schedule 4
Available as: desonide is available as a cream.
What does it do? Desonide relieves inflammation of the skin.
Overdose risk: low
Dependence risk: low
Is desonide available as a generic? no
Is desonide available on prescription only? yes
Stopping this medicine: do not stop using this medication abruptly as
it may cause a recurrence of the original symptoms being treated. Consult with
your doctor prior to discontinuing treatment.
Prolonged use: this medicine is not intended for long-term use.
Treatment should generally not exceed four weeks.
Consult your doctor before using this drug if:
- you have a bacterial, fungal or viral skin
- you have porphyria
- you have skin ulcers/broken skin
- you have acne or rosacea
Pregnancy: avoid. It is unknown how this medication may affect your
baby. Consult your doctor before using this drug, or if you are planning to fall
Breastfeeding: avoid. It is unknown how this medication may affect
your baby. Consult your doctor before use.
Porphyria: avoid. This medication may cause serious adverse effects.
Consult your doctor before use.
Infants and children: avoid. No data available for use in
The elderly: no special precautions need to be taken.
Driving and hazardous work: no special precautions need to be
Alcohol: no special precautions need to be taken.
Possible side effects
||Consult your doctor
||Only if severe
||In all cases|
Interactions are uncommon when desonide is used as directed.
A small overdose is no cause for concern. In case of intentional large
overdose, seek emergency medical attention.
Apply sparingly to the affected up to twice daily. Reduce number of
applications on improvement of symptoms.
This material is not intended to substitute medical advice, but is for
informational purposes only. Please consult a physician for
specific treatment and recommendations.