Meds and you

Updated 11 February 2013


Cefprozil is a broad spectrum antibiotic effective in treating a variety of bacterial infections.


Cefprozil is the active ingredient of Prozef.

General Information

Cefprozil is a broad spectrum antibiotic effective in treating a variety of bacterial infections. It is frequently prescribed to treat upper respiratory tract infections, including pharyngitis and tonsillitis, middle-ear infections, sinusitis, lower respiratory tract infections, including acute and chronic bronchitis, skin and soft tissue infections and urinary tract infections caused by organisms that are susceptible to cefprozil.

It is important to note that this medication is only effective against bacterial infections. If your infection is the result of a viral or fungal infection, it will be ineffective.

Antibiotic resistance - when bacteria develop the ability to defend themselves against the effect of an antibiotic - occurs frequently with many antibiotics. It mostly happens when patients do not complete the prescribed course in full, allowing bacteria to recover from treatment, and by using antibiotics for non-bacterial infections such as colds and flu.

Persons who are allergic to penicillin should take cefprozil with caution. Although it is not penicillin, cross-sensitivity - meaning that you may also be allergic to this drug - may occur.

How does cefprozil work?

Cefprozil weakens the bacterial cell wall and allows water to enter the cell, causing cells to burst.

Fast facts

Drug schedule: Schedule 4

Available as: Cefprozil is available as tablets and suspension

What does it do? This medication has an antibiotic action

Overdose risk: Low

Dependence risk: Low

Is cefprozil available as a generic? No

Is cefprozil available on prescription only? Yes

User information

Dietary advice: This medication may be taken with or without food.

Stopping this medicine: Do not stop taking this medication until you have finished the course as prescribed by your doctor - infection may recur with premature discontinuation.

Prolonged use: Cefprozil is usually given only for short courses of treatment.

Special precautions

Consult your doctor before using this drug if:

  • You have a kidney disease
  • You are allergic to other cephalosporins or penicillin
  • You are taking other medication.

Pregnancy: Avoid. It is unknown how this medication may affect your baby. Consult your doctor before using this drug, or if you are planning to fall pregnant.

Breastfeeding: Avoid. This medication is passed through breast milk and may affect your baby adversely. Consult your doctor before use.

Porphyria: Avoid. This medication may cause serious adverse effects. Consult your doctor before use.

Infants and children: This medication is safe for use in children at the recommended dose.

Elderly: Caution is advised in the elderly as adverse effects may be more severe.

Driving and hazardous work: Caution is advised, as use of this medication may lead to dizziness, light-headedness and/or sedation. Avoid such activities until you know how this medication affects you.

Alcohol: Concomitant use of alcohol with this medication is not advised.

Possible side effects

Side effect


Consult your doctor



Only if severe

In all cases




Stomach cramps



Nausea and vomiting



Rash/ hives/ itchy skin






Breathing difficulties



Swelling of face/ throat



Fever/ sweating



Bloody diarrhea




Drug interactions


Increased risk of warfarin toxicity

Non-steroidal anti-inflammatory drugs

Increased risk of bleeding


Drugs may counteract each other

Vancomycin/ aminoglycoside antibiotics

Increased risk of kidney toxicity

Oral contraceptives

Risk of contraceptive failure


Increased levels of antibiotic in body

Overdose action

A small overdose is no cause for concern. In case of intentional large overdose, seek emergency medical attention. Symptoms may include seizures, severe abdominal pain and vomiting.

Recommended dosage

Adults: 500 mg one to twice daily


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