advertisement
Updated 11 February 2013

Cefotaxime

Cefotaxime is a broad-spectrum antibiotic effective in treating a variety of bacterial infections.

0

Cefotaxime is the active ingredient of Adco-Cefotaxime, Austell-Cefotaxime, Claforan, Kefotax, Klafotaxim and Pharmacare-Cefotaxime.

General information

Cefotaxime is a broad-spectrum antibiotic effective in treating a variety of bacterial infections. It is frequently prescribed to treat infections of the urinary, gastro-intestinal and respiratory tract as well as certain sexually transmitted diseases and meningitis caused by organisms that are susceptible to cefotaxime.

It is important to note that this medication is only effective against bacterial infections - if your infection is the result of a viral or fungal infection, it will be ineffective.

Persons who are allergic to penicillin should take cefotaxime with caution. Although it is not a penicillin, cross-sensitivity - meaning that you may also be allergic to this drug - may occur.

How does cefotaxime work?

Cefotaxime weakens the bacterial cell wall and allows water to enter the cell, causing cells to burst.

Fast facts

Drug schedule: schedule 4

Available as: cefotaxime is only available as injection

What does it do? This medication has an antibiotic action

Overdose risk: low

Dependence risk: low

Is cefotaxime available as a generic? yes

Is cefotaxime available on prescription only? yes

Special precautions

Consult your doctor before using this drug if:

  • you have a kidney or liver disease
  • you are allergic to other cephalosporin antibiotics or penicillin
  • you have pseudomembrane colitis
  • you are taking other medication

Pregnancy: avoid. It is unknown how this medication may affect your baby. Consult your doctor before using this drug, or if you are planning to fall pregnant.

Breastfeeding: avoid. This medication is passed through breast milk and may affect your baby adversely. Consult your doctor before use.

Porphyria: avoid. This medication may cause serious adverse effects. Consult your doctor before use.

Infants and children: this medication should only be used as directed by your paediatrician.

The elderly: caution is advised in the elderly as adverse effects may be more severe.

Possible side effects

Side effect

Frequency

Consult your doctor

Common

Rare

Only if severe

In all cases

diarrhoea

x

x

stomach cramps

x

x

nausea and vomiting

x

x

rash/ hives/ itchy skin

x

x

confusion/light-headedness

x

x

convulsions

x

x

breathing difficulties

x

x

swelling of face/ throat

x

x

fever/ sweating

x

x

bloody diarrhoea

x

x

Interactions

Drug interactions

warfarin

increased risk of warfarin toxicity

non-steroidal anti-inflammatory drugs

increased risk of bleeding

chloramphenicol

drugs may counteract each other

vancomycin/ aminoglycoside antibiotics

increased risk of kidney toxicity

oral contraceptives

risk of contraceptive failure

probenecid

increased levels of antibiotic in body

Recommended dosage

Adults: 2 - 4 g daily

Children: only as prescribed by a paediatrician.

This material is not intended to substitute medical advice, but is for informational purposes only. Please consult a physician for specific treatment and recommendations.

 
More in Medical
Tretinoin
advertisement

Get a quote

advertisement

Read Health24’s Comments Policy

Comment on this story
0 comments
Add your comment
Comment 0 characters remaining

Live healthier

Knee pain relief »

Knee injuries Test your knee pain knowledge Symptoms of knee pain

Do you suffer from knee pain?

Do you suffer from recurrent knee pain? It could be osteoarthritis...

Vitamin wise »

Vitamins for HIV What to eat for vitamin B? Cut down on vitamins

Get your vitamins right

Find out which vitamin to use for which condition. Ask our Vitamin expert.