Meds and you

27 September 2013

Acipimox

Acipimox is a lipid-lowering medication. It reduces the amount of lipoproteins (LDL and VLDL) - the so-called "bad fats" in your body.

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Acipimox is the active ingredient of Olbetam capsules (Nappi code: 788643-002).

General information

Acipimox is a lipid-lowering medication. It reduces the amount of lipoproteins (LDL and VLDL) - the so-called "bad fats" in your body.

In South Africa acipimox is registered for the treatment of type IIa, IIb, IV lipid disorders (hyperlipidaemia).

For this medication to be effective, it has to be taken regularly, even if you do not notice an immediate effect.

Be sure to take acipimox after a meal.

How does acipimox work?

Acipimox prevents the release of fatty acids from fatty tissue and thereby indirectly decreases the production of VLDL an LDL in the liver.

Fast facts

Drug schedule: schedule 3

Available as: acipimox is available as capsules.

What does it do? Acipimox reduces high levels of fat in the body.

Overdose risk: low

Dependence risk: low

Is acipimox available as a generic? no

Is acipimox available on prescription only? yes

User information

Dietary advice: it is advised that this drug be used as adjunctive therapy to a low-fat diet

Stopping this medicine: do not stop taking this drug without consulting your doctor.

Prolonged use: regular monitoring of liver and kidney function is advised.

Special precautions

Tell your doctor before using this drug if:

  • you have a stomach ulcer
  • you have a kidney disease
  • you are pregnant

Pregnancy: avoid. It is unknown how this medication may affect your baby. Consult your doctor before using this drug, or if you are planning to fall pregnant.

Breastfeeding: avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.

Porphyria: avoid. It is unknown how this medication may affect your condition. Consult your doctor before use.

The elderly: no special precautions need to be taken.

Driving and hazardous work: no special precautions need to be taken.

Alcohol: avoid concomitant use of alcohol with this medication.

Possible side effects

 

 

Side effects Frequency   Consult your doctor  
  Common Rare Only if severe In all cases
headache x   x  
rash x   x  
itching x   x  
diarrhoea x   x  
abdominal  pain x   x  
heartburn x   x  
dry eyes x   x  
flushing x   x  
broncho-constriction   x   x
facial swelling   x   x

 

Interactions

Drug interactions

No significant drug interactions are currently known.

Overdose action

A small overdose is no cause for concern. In case of intentional large overdose, seek emergency medical attention.

Recommended dosage

Adults, oral: 500-750 mg/day in divided doses (with a meal)

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This material is not intended to substitute medical advice, but is for informational purposes only.

               Please consult a physician for specific treatment and recommendations.

 

 

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