Diabetes

Question
Posted by: Me | 2012-07-05

Q.

Type 2 Diabetic

I am using glucophase 850 x 2 in the morning, insolinen Novarapid 3 x day (30) and 3 x glucophase 1000 before meals and then Levemir (46) at night. Can there be any damage course ? my readings inproved since I take the glucophase 1000 3 x a day.


Expert's Reply

A.

Diabetes expert

Dear Me
If I calculate correctly, then you are on about 4700mg of metformin a day, which is an unusually high dose. The effect of metformin reaches a plateau at about 2500mg a day, in other words you can increase the dose above this, but don’t get any more effect. The question of whether it is bad or not is not easy to answer, as there aren’t long term studies on such high doses, however, if you have no other medical problems like kidney or heart , then it should be okay , although you may well get more side effects like diarrhea, bloating and nausea.

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C.

Posted by: Diabetes Expert | 2012-07-11

Dear Me
If I calculate correctly, then you are on about 4700mg of metformin a day, which is an unusually high dose. The effect of metformin reaches a plateau at about 2500mg a day, in other words you can increase the dose above this, but don’t get any more effect. The question of whether it is bad or not is not easy to answer, as there aren’t long term studies on such high doses, however, if you have no other medical problems like kidney or heart , then it should be okay , although you may well get more side effects like diarrhea, bloating and nausea.

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