Diabetes

Question
Posted by: samantha | 2012/06/18

Q.

pcos

hi

i am a 27yr old indian female i have been recently diagnosed with diabetes type 2 and i have pcos. i have been trying to fall pregnant for the past 3 years as i was on glucophage but i was not successful trying to concieve. i recently visited a endocrinologist and was put on glucophage 500mg xr and aldactone 25mg and cipla - pioglitazon 15mg. will this assist in me falling pregnant. and is the pioglitazone safe medication to take.

thank you

Expert's Reply

A.

Diabetes expert

Dear Samantha
Both aldactone and pioglitazone have a category C rating by the FDA which means animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Regarding glucophage, this has not been shown to be unsafe in pregnancy, and therefore would be fine to use. With regards to benefit in terms of assisting in falling pregnant, aldactone and pioglitazone will not help, and there as there is no benefit and potentially there is harm , I would suggest talking to your endocrinologist again.

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2
user comments

C.

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Reply to Rockstar
Posted by: Diabetes Expert | 2012/06/25

Dear Samantha
Both aldactone and pioglitazone have a category C rating by the FDA which means animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Regarding glucophage, this has not been shown to be unsafe in pregnancy, and therefore would be fine to use. With regards to benefit in terms of assisting in falling pregnant, aldactone and pioglitazone will not help, and there as there is no benefit and potentially there is harm , I would suggest talking to your endocrinologist again.

Reply to Diabetes Expert

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