Diabetes

Question
Posted by: Laura | 2012/03/21

Q.

Metformin

I have Insulin Resistance, PCOS and I am hypoglycemic. Would you advise that I take Metformin? And if so, what should the dosage be?

Expert's Reply

A.

Diabetes expert

Dear Laura

The use of metformin in PCOS has dwindled with time. Its main use is for a patient who is pre-diabetic and glucose levels are going up regardless of lifestyle changes. It doesn’t help with irregular periods and has limited effect on lowering testosterone levels or weight loss. The reason why it gets used is for its effect on insulin resistance which is a core component of PCOS. Its use as a fertility drug has also become less with time, as there are better alternatives. If it has been prescribed for you, then I would suggest getting up to a good dose of 850mg twice a day. The best overall treatment for PCOS is weight loss.

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user comments

C.

Posted by: Diabetes Expert | 2012/03/28

Dear Laura

The use of metformin in PCOS has dwindled with time. Its main use is for a patient who is pre-diabetic and glucose levels are going up regardless of lifestyle changes. It doesn’t help with irregular periods and has limited effect on lowering testosterone levels or weight loss. The reason why it gets used is for its effect on insulin resistance which is a core component of PCOS. Its use as a fertility drug has also become less with time, as there are better alternatives. If it has been prescribed for you, then I would suggest getting up to a good dose of 850mg twice a day. The best overall treatment for PCOS is weight loss.

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