Your two daughters would be at higher risk, but if they don't have classic symptoms(weight loss, tiredness, and increased thirst and passing of urine) I wouldn't do routine testing, as they may never develope diabetes, and would be subjected to unnecessary stress and testing. Suggest rather that they watch their diet and maintain a healthy weight. Regarding type 1 diabetes there are studies to show that you can predict those at increased risk by measuring antibodies against the pancreas,but despite this we have been unable to stop the onset.
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