Updated 30 September 2015

6 frequently asked questions about cough medicine for kids

Treating a child with a cough can be tricky, especially when it comes to choosing the right type of medication. Here are answers to some of the questions most commonly asked by parents.


1. Which cough and cold remedies for children should be carefully considered before use?

Over-the-counter (OTC) cough and cold remedies (including oral preparations and nasal drops) containing the following ingredients:

- Nasal decongestants (pseudoephedrine, ephedrine, phenylephrine, oxymetazoline and xylometazoline),

- Antihistamines (diphenhydramine,chlorphenamine, bromopheniramine, promethazine, triprolidine and doxylamine),

- Antitussives (dextromethorphan and pholcodine), and

- Expectorants (guaifenesin and ipecacuanha).

2. Do cough and cold medicines for children really work?

There is no robust evidence that they work. At the time that many over-the-counter products were authorised it was assumed that medicines worked the same way in adults and children and dosing in children was estimated from that in adults; and clinical trials were not routinely done in children.

However, we better understand now that children are not ‘little adults’. Although some of the products have been available for many years, we are now working towards medicines properly designed and tested for children. Research is needed on how effective the medicines are in children over 6.

3. Why shouldn't OTC cough mixtures be given to children below the age of 6?

Despite the fact that these medicines have been used for many years in children there is no robust evidence that they work, and very rarely they can cause side effects, such as allergic reactions, effects on sleep or hallucinations.

The risks of these effects reduces in older children because they weigh more, they get fewer colds and can say if the medicine is doing any good. Body weight can affect how medicines work, and some children between 2 and 6 years may weigh the same as other children who are less than 2 years.

On reviewing all the evidence available, the CHM has advised that the balance of risks and benefits is unfavourable in children under 6.

In March 2008 the CHM gave advice based on a preliminary review that children under two years of age may be at particular risk from any side effects of these medicines, especially if given in overdose, because of their small size, and that these medicines should not be used in under two's. 

4. Do I need to worry if I have just given one of these medicines to my child?

Provided that the child has been given the dose as recommended on the bottle, you do not need to worry; but if you have concerns about the condition of your child, you should contact a health professional. 

You should review the medicines which you have, to see whether there are any which you no longer need: these can be taken to any pharmacy for disposal.

5. So what should we do when a child has a cough/cold?

Cough and colds are self limiting conditions and will usually get better by themselves. Simple measures such as ensuring your child has plenty to drink and gets enough rest will help. Paracetamol or ibuprofen can also be used to reduce your child’s temperature.

For young babies, particularly those who are having difficulty feeding, nasal saline drops are available to help thin and clear nasal secretions. If your child is over the age of one, a warm drink of lemon and honey may help to ease a cough.

If your child is not getting better after 5 days, ask a health professional for advice.

6. Are these products safe and effective for adults? Should adults still use them?

Standards for clinical trials have become much stricter since many of the early studies on cough and cold products. However, there is not a safety concern with the use of these products in adults as long as dosage instructions are followed. 


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Cough Expert

Professor Keertan Dheda has received several prestigious awards including the 2014 Oppenheimer Award, and has published over 160 peer-reviewed papers and holds 3 patents related to new TB diagnostic or infection control technologies. He serves on the editorial board of the journals PLoS One, the International Journal of Tuberculosis and Lung Disease, American Journal of Respiratory and Critical Medicine, Lancet Respiratory Diseases and Nature Scientific Reports, amongst others. Read his full biography at the University of Cape Town Lung Institute.

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