Breast cancer

20 May 2008

Breast cancer gene ups male risk

Men in families that carry the breast cancer gene BRCA2 are at increased risk for prostate cancer, say Australian researchers.

Men in families that carry the breast cancer gene BRCA2 are at increased risk for prostate cancer, say Australian researchers who've been investigating families with multiple cases of breast and ovarian cancer for 10 years.

"We discovered that a man with a genetic fault in BRCA2 has almost four times the risk of developing prostate cancer than men in the general population. The BRCA2-prostate cancer that arises in these men also tends to be more aggressive," researcher Heather Thorne said.

She said it's hoped the finding, published in the journal Clinical Cancer Research, will encourage men to assess their genetic risk in the same way women do with breast and ovarian cancer.

"If a man comes from a family with multiple cases of breast or ovarian cancer, or knows there is a BRCA2 gene mutation running in their family, they may be at increased risk of developing prostate cancer," Thorne said, AFP reported.

"These men can go to (clinic) and discuss genetic testing, and be given appropriate advice if they are found to be at increased risk." – (HealthDay News, May 2008)

Read more:
Men with breast cancer high risk
DNA test to ID prostate cancer


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Dr Gudgeon qualified in Birmingham, England, in 1968. She has more than 40 years experience in oncology, and in 1994 she founded her practice, Cape Breast Care, where she treats benign and malignant breast cancers. Dr Boeddinghaus obtained her qualification at UCT Medical School in 1994 and her MRCP in London in 1998. She has worked extensively in the field of oncology and has a special interest in the hormonal management of breast cancer. She now works with Dr Gudgeon at Cape Breast Care. Read more.

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