Baffled by basophils, ignorant about IgE? Here's what it all means.
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Allergen: an allergy-causing substance;
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Antibody: a B-cell produced protein molecule made in response to, and reactive with, a specific antigen;
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Antigen: a substance capable of causing the production of antibodies and then reacting specifically with these antibodies;
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B-cell (B-lymphocyte): a type of white blood cell capable of producing antibodies;
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Basophil: a white blood cell containing histamine and other allergy mediators;
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Histamine: a chemical present mainly in mast cells that, when released, causes many of the symptoms of allergy;
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IgE: the type of antibody most instrumental in allergic reactions;
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Lymph nodes: small organs within the lymph system located at the intersections of lymph channels;
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Lymphocyte: a type of white blood cell instrumental in antibody production;
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Mast cell: a type of cell containing histamine and other allergy mediators instrumental in the allergic response.
(Health24, updated February 2010)
Allergy Society of South Africa (ALLSA)