Meningioma, the most common primary brain tumour and accounts for about 33% of all primary brain tumours. The most consistently identified environmental risk factor for meningioma is exposure to ionising radiation.
In the largest study of its kind, researchers from Brigham and Women's Hospital (BWH), Yale University School of Medicine, Duke University, UCSF and Baylor College of Medicine have found a correlation between past frequent dental x-rays, which are the most common source of exposure to ionising radiation in the US, and an increased risk of developing meningioma. These findings are published in the issue of Cancer.
"The findings suggest that dental x-rays obtained in the past at increased frequently and at a young age, may be associated with increased risk of developing this common type of brain tumour," said Elizabeth Claus, MD, PhD, a neurosurgeon at BWH and Yale University School of Medicine at New Haven. "This research suggests that although dental x-rays are an important tool in maintaining good oral health, efforts to moderate exposure to this form of imaging may be of benefit to some patients."
Claus and her colleagues studied data from 1 433 patients diagnosed with meningioma between 20 and 79 years of age between May 2006 and April 2011 and compared the information to a control group of 1350 participants with similar characteristics.
Increased risk of meningioma
They found that patients with meningioma were twice as likely to report having a specific type of dental x-ray called a bitewing exam, and that those who reported having them yearly or more frequently were 1.4 to 1.9 times as likely to develop a meningioma when compared to the control group.
Additionally, researchers report that there was an even greater increased risk of meningioma in patients who reported having a panorex x-ray exam. Those who reported having this exam taken under the age of 10, were 4.9 times more likely to develop a meningioma compared to controls.
Those who reported having the exam yearly or more frequently than once a year were nearly three times as likely to develop meningioma when compared to the control group. "It is important to note that the dental x-rays performed today use a much lower dose of radiation than in the past," said Claus.
According to background information in the study, The American Dental Association's statement on the use of dental radiographs emphasises the need for dentists to examine the risks and benefits of dental x-rays and confirms that there is little evidence to support the use of dental x-rays in healthy patients at preset intervals.
(EurekAlert, April 2012)