Posted by: Cind' s | 2009-01-14

What can we do

We have just found out that my husband has Sertoli Only Cell Syndrome, what can be done to still help us have a baby? Is there treatment?

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Our expert says:
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Dear Cind’s

Unfortunately the prognosis in this situation is not very good. However, depending on the extent of testicular exploration, occasionally certain areas within the testicle maybe of better prognosis and it maybe valuable as a last resort to have a radical exploration of both testicles with multiple biopsies taken. Should no sperm or precursors be noted by this method then unfortunately the donor option needs to be explored.

Answered by: Dr. M.I. Cassim

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Our users say:
Posted by: c | 2009-01-18

Sertoli-cell-only (SCO) syndrome, also called germ cell aplasia, describes a condition of the testes in which only Sertoli cells line the seminiferous tubules. Typically, these men present between age 20-40 years for evaluation of infertility and are found to be azoospermic, a term describing the absence of sperm in the ejaculate. Physical examination is often unremarkable, and the diagnosis is made based on testicular biopsy findings. While investigation to identify a cause of SCO syndrome is ongoing, the etiology and mechanism of this process are currently unknown. No known effective treatment exists. SCO syndrome presents during the evaluation of azoospermia in couples having difficulty in initiating a pregnancy. These men typically present with infertility as the only symptom.

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