Our expert says:
compare the two hands - does it seem as if the sore one's thumb muscle is less bulky than the other side ( look on the palm side) - this could be an indication of a nerve entrapment in the arm. If the area is red and swollen, you may have infection in the webspace. You can also get referred pain to that area because of inflammation in the thumb muscle (short abductor of the thumb muscle) Try an anti-inflammatory like ibuprofen but it if persists let your doctor have a look to see if you need referral to an orthopedic surgeon
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