Our expert says:
It happens, but it's really uncommon for someone's depression not to respond to such treatment. The first or second AD tried might not work well enough - each of them suits only around 70 % of those who try it. Some people do respond better to a combination of ADs, as they each tend to have a different way of affecting the relevant brain chemicals. Such problems as you describe tend to be called "Treatment-Resistant Depression", and calls for a thorough review and a series of planned trials of different meds, and also other meds called "adjuvants" which may help an AD tyo work more effectively.
Presumably they will also have checked other possible physical aspects of your situation, as such things as hormone changes, or low thyroid conditions, may need to be dealt with as they otherwise can confound AD treatment.
I understand how horribly discouraging all of this has been for you, but it is really worth persisting, and continuing the struggle to find the right way to lift this depression. I can assure you, from loads of experience and research studies, that your family and children are far better off having you around, even while you are seriously depressed, than without you. Stay alive and stay strugling for their sake as well as your own.
The problem may seem interminable, but a year isn't excessively long in the sense that albeit rare, some people need a year or two of adjusting their chemistry AND working on their psychology ( Cognitive-Behaviour Therpay seems the most likely to be effective ) before things come right. You are worth it.
The sense of hopelessness, and the loss of pleasure and interest is sadly typical of Depression, and should lift as the illness starts to subside.
Do keep in touch with us on the forum, if you wish, and let us know what various treatments you have tried, and how things are going on for you
The information provided does not constitute a diagnosis of your condition. You should consult a medical practitioner or other appropriate health care professional for a physical exmanication, diagnosis and formal
advice. Health24 and the expert accept no responsibility or liability for any damage or personal harm you may suffer resulting from making use of this content.