Our expert says:
Firstly it is important that you visit your gynaecologist as your symptoms may well be the first sign of ovarian Hyperstimulation syndrome (OHSS) which can be of a serious consequence. Abdominal distention, weight gain, fluid retention and nausea and to some extent shortness of breath all part of the symptoms and if you have these I would recommend going to your gynaecologist first. Secondly Glucophage may also cause gastric symptoms such as nausea and irritability of the bowel and maybe partly responsible for what you are experiencing in the absence of a pregnancy. I would certainly not recommend using dosages of Fertomid as high as 150 as it is well documented that high doses of Clomiphene citrate can have a negative bearing on the lining and hence the lining becomes paradoxically thinner despite more estrogen being produced from the ovaries. It is very unlikely that Estrofem will enhance or improve the outcome of the situation and hence the use of high dose of Clomiphene citrate should be discouraged. I would suggest that you consult with a fertility specialist as it may be necessary at this point to change your treatment protocol to include injectable stimulation agents and also due to your PCOS to monitor you carefully for ovarian cyst formation and Hyperstimulation syndrome.
Answered by: Dr M.I. Cassim
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