Our expert says:
The problem of recurrent first trimester miscarriages or blighted ovum pregnancies is certainly a requirement for further investigation. In the vast majority of cases an underlying chromosomal or genetic problem can be suspected and can be very difficult to diagnose or confirmed unless some form of embryo testing is undertaken. Even with embryo testing via pre-genetic diagnosis (PGD) it can be fairly difficult to exclude all possibilities since there are numerous genetic probabilities and one needs to known what is being suspect so as to investigate accordingly. However as a routine both you and your partner may need to undergo some form of genetic screening for the more common or likely possibilities of chromosome carrier states. Other lines of investigations would include blood tests or autoimmune disorders as well as other hormonal factors such as thyroid abnormalities or metabolic problems. Abnormalities of the uterus should be investigated as well and an infection screen should be undertaken. Should all these tests prove to be negative then it might be advisable to consider invitro fertilization and careful embryo selection as your last option.
Answered by: Dr M.I. Cassim
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