Our expert says:
The use of Depo between IVF cycles is certainly not advised as the effect of Depo may persists for much longer than anticipated and in some cases up to two years after stopping the injections. The effect is particularly pronounced on the endometrium (lying of the womb), which directly impact on the implantation of embryos and therefore will have a negative impact on subsequent IVF cycles. Depo is sometimes used to control endometriosis but there are better and more sophisticated drugs available to do the same or be it more expensive. These new generation drugs do not have the same drawbacks as Depo in terms of impact on the endometrium as well as on the success of ovulation induction (success of producing eggs in an IVF cycle). The abnormal bleeding is a side effect of the Depo and may need to be dealt with by using additional hormonal medication. In some incidences the bleeding problem rectifies itself with further doses of Depo but in my opinion Depo should be avoided if future IVF cycles are planned.
Answered by: Dr M.I. Cassim
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