Our expert says:
Mabthera is a monoclonal antibody. This is a protein ( antibody) that binds to a specific receptor (area) on the surface of a specific type of white blood cell called a B cell. The antibody causes the death of the B cells, reducing the number of B cells in the body. B cells trigger the abnormal inflammatory response that causes the damage and symptoms of RA. Because it is "targeted treatment" (works only on the B cells) unlike metothrexate, it is not toxic to any of the other blood cells and does not affect your immunity otherwise. Side effects are allergic reaction to the infusion, dizziness, hypertension, sore throat.
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