Our expert says:
OK, these things aren't precise, and some people start feeling better in some ways even earlier. But because the benefits of an antidepressant (AD) involve specific changes within the brain, which take around 2 weeks to happen. But this is appoximate, not guaranteed ( only around 70 % of folks respond really well the the first AD they try ) and also evidence shows that the improvements are often noticed first by the family and friends who know the person, rather than by the person themselves.
Various side-effects are typical of any drug, some are unlikely. Hip pain ( I know from personal experience ) can be awful, but isn't recognized as a side-effect of an AD drug.
Your doctor should see you to review progress after around 2 weeks from starting the drug, and discuss with you whether this specific drug is showing convincing evidence of helping you, or whether a different drug should be considered instead.
Nobody can expect any one drug to suit everyone they see, so any good doctor works with several alternative ADs, to handle just this sort of situation
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