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Question
Posted by: Hope* | 2010/05/31

Confused

Hi CS,

Please tell me if I understand this correctly.

If one takes AD''s to increase serotonin levels, the serotonin levels could become unbalanced and therefore one would need dopamine to slowly keep the balance?

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Our expert says:
Expert ImageCyberShrink

Actually, it's a good deal more scomplex than that QUite a number of chemicals are involved in our normal brain function, and imbalances in several of them seem to play a part in Depression as well as other disorders. Other chemicals like Noradrenaline used to be the focus of attention ( because early ADs affected those lvels ) then Serotonin was recognized as significant, when drugs to affect that chemical became available.
Dopamine plays a part in a number of conditions, and so to several other chemicals, such as GABA. Just beginning to become available are antidepressants working primarily on these other chemical systems.
Just to make it still more complex, drugs affecting one of these chemicals often also then indirectly affect the others.
If one of the chemicals is under-represented, either with their being less of it or with it being less active or available, for various reasons, you don't necessarily need more of other chemicals - if the less-available chemical increases, it will get back in balance with others that are already at appropriate levels.

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Our users say:
Posted by: cybershrink | 2010/05/31

Actually, it's a good deal more scomplex than that QUite a number of chemicals are involved in our normal brain function, and imbalances in several of them seem to play a part in Depression as well as other disorders. Other chemicals like Noradrenaline used to be the focus of attention ( because early ADs affected those lvels ) then Serotonin was recognized as significant, when drugs to affect that chemical became available.
Dopamine plays a part in a number of conditions, and so to several other chemicals, such as GABA. Just beginning to become available are antidepressants working primarily on these other chemical systems.
Just to make it still more complex, drugs affecting one of these chemicals often also then indirectly affect the others.
If one of the chemicals is under-represented, either with their being less of it or with it being less active or available, for various reasons, you don't necessarily need more of other chemicals - if the less-available chemical increases, it will get back in balance with others that are already at appropriate levels.

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